What does caco- mean?

caco- meaning in Etymology Dictionary

before vowels cac-, word-forming factor meaning "bad, sick, poor" (as in cacography, the alternative of calligraphy), from Latinized kind of Greek kako- a hard-working prefix in ancient Greek, from kakos "bad, evil," considered by etymologists most likely become related to PIE *kakka- "to defecate" (see caca).