What does Animus Headache mean?

Animus Headache meaning in Urban Dictionary

The annoyance after playing a video game for an extended period of time. This originates from the video game Assassin's Creed II in which the primary personality is put into a device known as the Animus which allows him to relive the thoughts of forefathers and towards the end of game, experiences some side-effects such as headaches and hallucinations.