Amyotrophic lateral sclerosis 1 meaning in Medical Dictionary
ALS1. A type of amyotrophic lateral sclerosis (ALS) passed down in an autosomal principal fashion and caused by mutation in superoxide dismutase-1 gene (SOD1) on chromosome 21q22.1. About 15 to 20percent of familial ALS is type 1 (ALS1). Sporadic instances of ALS are sometimes because of brand-new mutation into the SOD1 gene.