Of London on Bear Creek, an affluent of Sydenham River, and on the Grand Trunk and Michigan Central railways.
As his model in medical methods, Sydenham repeatedly and pointedly refers to Hippocrates, and he has not unfairly been called the English Hippocrates.
A physician of Plymouth, John Huxham (1694-1768), made researches on epidemic fevers, in the spirit of Sydenham and Hippocrates, which are of the highest importance.
Hippocrates had no opportunity of verification by necropsy, and Sydenham ignored pathology; yet the clinical features of many but recently described diseases, such, for example, as that named after Graves, and myxoedema, both associated with perversions of the thyroid gland, lay as open to the eye of physicians in the past as to our own.
The extent to which his practice was influenced by this and other a priori conceptions prevents us from classing Sydenham as a pure empiric; but he had the rare merit of never permitting himself to be enslaved even by his own theories.
Mead was the pupil of the equally popular and successful John Radcliffe (1650-1714), who had acquired from Sydenham a contempt for book-learning, and belonged to no school in medicine but the school of common sense.
Their English contemporaries and successors, John Freind, William Cole, and Richard Mead, leaned also to mechanical explanations, but with a distrust of systematic theoretical completeness, which was perhaps partly a national characteristic, partly the result of the teaching of Sydenham and Locke.
The collection has been submitted to the closest criticism in ancient and modern times by a large number of commentators (for full list of the early commentators, see Adams's Genuine Works of Hippocrates, Sydenham Society, i.