In the yeast cell the nucleus is represented by a homogenous granule, probably of a nucleolar nature, surrounded and perhaps to some extent impregnated by chromatin and closely connected with a vacuole which often has chromatin at its periphery, and contains one or more volutin granules which appear to consist of nucleic acid in combination with an unknown base.
In the peritoneum, by injections of nonpathogenic organisms, peptone, nucleic acid and various other substances.
It appears to have some of the characteristics of nucleic acid, and according to Meyer may be a combination of nucleic acid with an unknown organic base.
Recent researches have shown that the nucleic acid can be broken up by chemical means into a number of different compounds or bases.
Nucleic acid is at present of unknown constitution; decomposition products are: phosphoric acid, uracil or 2.6-dioxy-pyrimidin,1 cytosin or 2-oxy-6-amino-pyrimidin, thymin (nucleosin) or 2.6-dioxy-5-methyl pyrimidin hypoxanthin 1 or 6-oxypurin, xanthin or 2.6-dioxypurin, adenine or 6 amino-purin, guanine or 2amino-6-oxypurin, pentoses (l-xylose), laevulinic acid, ammonia, etc. The nucleic acids vary with the source of the proteids, there being considerable differences in chemical composition.
It appears to be a combination of a protein with nucleic acid.