The acute bed-sore is, in some cases, a true trophic lesion occurring, as it may, on parts not subjected to continuous pressure or irritation.
But the practitioner must be assured that neither valvular lesion nor degeneration of the myocardium is present.
Certain skin diseases, as psoriasis, pemphigus and occasionally chronic eczema, are much benefited by its use, though occasionally a too prolonged course will produce the very lesion for which under other circumstances it is a cure.
The sensation of pain is felt in the brain, and the cause of it may be in the sensory centres of the brain alone, as in cases of hysterical pain, with no lesion to cause it.
Both these preparations should only be used in cases where it is possible to exclude any tuberculous foci, or by their action in breaking down protective fibrous tissues they may cause a quiescent lesion to become active.
The common variety of bed-sore is the result of continuous pressure on and irritation of the skin, the vitality and resisting power of which are lowered by a lesion of the cord cutting off the trophic supply to the skin affected.
Syphilitic lesion of the arteries, and likewise of other fibrous tissues, often involves grave consequential damage to nervous structures fed or supported by such parts.
A post mortem examination was held, which showed not only grave derangement in the stomach and other organs, but a serious lesion of the brain.