For some time longer the Tatars remained troublesome neighbours, capable of invading and devastating large tracts of Russian territory and of threatening even the city of Moscow, but the Horde was now broken up into independent and mutually hostile khanates, and the Moscow diplomatists could generally play off one khanate against the other, so that there was no danger of the old political domination being re-established.
From the time of his first introduction to Tycho he had devoted himself to the investigation of the orbit of Mars, which, on account of its relatively large eccentricity, had always been especially recalcitrant to theory, and the results appeared in Astronomia nova ainoXayrgrii, seu Physica coelestis tradita commentariis de motibus stellae Martis (Prague, 1609).
It is the headquarters of the Devonshire sea-fisheries, having also a large coasting trade.
Many of the species attain a large size, and all are of very rapid growth.
The collections of Antoine Laurent de Jussieu, his son Adrien, and of Auguste de St Hilaire, are included in the large herbarium of the Jardin des Plantes at Paris, and in the same city is the extensive private collection of Dr Ernest Cosson.
The culture of the Homeric Achaeans corresponds to a large extent with that of the early Iron Age of the upper Danube (Hallstatt) and to the early Iron Age of upper Italy (Villanova).
In acute mania it acts like hyoscyamine in producing sleep. In large doses stramonium is a narcotic poison producing the wellmarked stages of exaltation of function, diminution of functional activity, and later loss of function, sinking into coma and paralysis.
A pantheist may believe in Law of Nature and go no further; a theist who accepts Law of Nature has a large instalment of natural theology ready made to his hand; including an idealist, or else an intuitionalist, scheme of ethics.
In 1766 he received a gold medal from the Academy of Sciences for an essay on the best means of lighting a large town; and among his early work were papers on the analysis of gypsum, on thunder, on the aurora and on congelation, and a refutation of the prevalent belief that water by repeated distillation is converted into earth.
At Mira is a large candle factory.