Pfeiffer was the first to show that this occurred when the bacterium was injected into the peritoneal cavity of the animal immunized against it, and also when a little of the serum of such an animal was injected with the bacterium into the peritoneum of a fresh, i.e.
He immunized 40 persons without mishap and with no more unpleasant results than those occurring after vaccination.
Various observers had previously found that the serum of an animal immunized against (a) Lysogenic action.
Immunity against toxins also became a subject of investigation, and the result was the discovery of the antitoxic action of the serum of animals immunized against tetanus toxin by E.
The serum of an animal thus actively immunized has powerful protective properties towards another animal, the amount necessary for protection being sometimes almost inconceivably small.
The second - passive immunity - is produced by the transference of a quantity of the serum of an animal actively immunized to a fresh animal; the term is applied because there is brought into play no active change in the tissues of the second animal.
One of the most remarkable practical outcomes of germ-pathology, however, has been the production of the immunized sera now employed so extensively in the treatment of diphtheria and other contagious diseases.
The serum of an animal immunized against the bacterium) was added to a fluid culture of this bacillus, growth formed a sediment instead of a uniform turbidity.
The virus cannot live in immunized individuals, nor in nature.