His father, the natural son of a grandmaster of the Teutonic order, was Wilhelm Bombast von Hohenheim, who had a hard struggle to make a subsistence as a physician.
Here are the well preserved ruins of a former castle of the Brethren of the Sword, afterwards (from 1237) of the grandmaster of the Teutonic Knights.
Andreas (1514-1559) was a physician of some repute, but through his influence with Albert of Brandenburg, last grandmaster of the Teutonic order, and first Protestant duke of Prussia, became an outstanding figure in the controversy associated with Andreas Osiander whose daughter he had married.
Under the increasing pressure of Russia (Muscovy) the Teutonic Knights in 1561 found it expedient to put themselves under the suzerainty of Poland, the grandmaster Gotthard Kettler (d.
In 1795, as grandmaster of the Masonic fraternity, he laid the cornerstone of the new State House in Boston, and in this year also founded the Massachusetts Charitable Mechanic Association, becoming its first president.