The bark has been employed for dyeing yellow and for tanning, and was formerly in popular repute as a febrifuge and tonic. The powder of the dried nuts was at one time prescribed as a sternutatory (to encourage sneezing) in the Edinburgh Pharmacopoeia.
That hitherto adopted by the Indian Government for the preparation of the cinchona febrifuge (see below) is simple, but the whole of the alkaloid present in the bark is not obtained by it.
In consequence of the high price of the alkaloid an attempt was made some years ago by the Government of India to manufacture from cinchona bark a cheap febrifuge which should represent the alkaloids contained in the bark and form a substitute for quinine.
The cultivation of the cinchona, several species of which have been introduced from South America and naturalized in the Sikkim Himalaya, promises to yield at a comparatively small cost an ample supply of the febrifuge extracted from its bark.
The species between Caravaya and the headwaters of the Huallaga yield very little of the febrifuge alkaloid.
The substance was discovered about the year 1835 by Hugh Rodie, a surgeon in Demerara, who used it as a febrifuge in.
This is also the case with the cinchona febrifuge prepared from C. succirubra.
The sulphate of quinine and the cinchona febrifuge thus produced are issued for the most part to medical officers in the various provinces, to gaols, and to the authorities of native states; but a large and increasing amount is disposed of in the form of 5-grain packets, costing a farthing each, through the medium of the post-offices.