As an exegete Theodoret belongs to the Antiochene school, of which Diodorus of Tarsus and Theodore of Mopsuestia were the heads.
On this method the sacred writings are regarded as an inexhaustible mine of philosophical and dogmatic wisdom; in reality the exegete reads his own ideas into any passage he chooses.
As an exegete he exercised a powerful, and on the whole a beneficial, influence on theological investigation.
This second phase of the activity of the school closes with the comprehensive labours of Alexander of Aphrodisias (Scholarch, c. 200), the exegete par excellence, called sometimes the second Aristotle.
He understood it to be the first duty of an exegete to ascertain the meaning of the writer, and he showed that this could be done by the use of grammar and history and the historical imagination.
Lucian the great exegete of Antioch and his school derived their inspiration from Paul, and he was through Lucian a forefather of Arianism.
As an exegete and biblical critic no less than as a grammarian he has left his abiding mark.