Nitrite of amyl has the power of dilating the arteries; it has consequently been employed with much success in lowering the blood pressure and removing the pain in angina pectoris.
In organic chemistry he published papers on the decomposition of ammonium oxalate, with formation of oxamic acid, on amyl alcohol, on the cyanides, and on the difference in constitution between nitric and sulphuric ether.
Sodium in boiling amyl alcohol reduces it to aromatic tetrahydro-a-naphthylamine, a substance having the properties of an aromatic amine, for it can be diazotized and does not possess an ammoniacal smell.
Thus amyl acetate is used as an imitation of the jargonelle-pear flavour; amyl valerate replaces apple flavour, and a mixture of ethyl and propyl butyrates yields the so-called pine-apple flavour.
As an example may be taken the use of nitrite of amyl in angina pectoris.
The following monatomic alcohols receive special treatment under their own headings: - Alcohol (Ethyl), Allyl Alcohol, Amyl Alcohols, Benzyl Alcohol, Butyl Acohols, Methyl Alcohol, and Propyl Alcohols.
Referring to the esters C9H1802 previously mentioned, it is seen that the highest boilingpoints belong to methyl octoate and octyl formate, the least symmetrical, while the minimum belongs to amyl butyrate, the most symmetrical.
In this process the amine salt is dissolved in absolute alcohol and diazotized by the addition of amyl nitrite; a crystalline precipitate of the diazonium salt is formed on standing, or on the addition of a small quantity of ether.
Sodium nitrite, ethyl nitrite, amyl nitrite) cause relaxation of involuntary muscular fibre and therefore relieve the asthmatic attacks, which depend upon spasm of the involuntary muscles in the bronchial tubes.
A similar product is obtained by oxidizing fermentation amyl alcohol with chromic acid.