Van Leeuwenhoek discovered bacteria, and it was soon found that however carefully organic matter might be protected by screens, or by being placed in stoppered receptacles, putrefaction set in, and was invariably accompanied by the appearance of myriads of bacteria and other low organisms. As knowledge of microscopic forms of life increased, so the apparent possibilities of abiogenesis increased, and it became a tempting hypothesis that whilst the higher forms of life arose only by generation from their kind, there was a perpetual abiogenetic fount by which the first steps in the evolution of living organisms continued to arise, under suitable conditions, from inorganic matter.