The results clearly show that there is loss of receptor function in patients with asthma during a naturally acquired virus infection.
If I knew for a certainty that a man was coming to my house with the conscious design of doing me good, I should run for my life, as from that dry and parching wind of the African deserts called the simoom, which fills the mouth and nose and ears and eyes with dust till you are suffocated, for fear that I should get some of his good done to me--some of its virus mingled with my blood.
Simpson in his Report on the Causes of the Plague in Hong Kong (1903) reports the endemicity of the plague in that colony to be maintained by (a) infection among rats often connected with infectious material in rat runs or in houses, the virus of which has not been destroyed, (b) retention of infection in houses which are rat-ridden, and (c) infected clothing of people who have been ill or died of plague.
Long before any clear ideas as to the relations of Schizomycetes to fermentation and disease were possible, various thinkers at different times had suggested that resemblances existed between the phenomena of certain diseases and those of fermentation, and the idea that a virus or contagium might be something of the nature of a minute organism capable of spreading and 1 Cladothrix dichotoma, for example, which is ordinarily a branched, filamentous, sheathed form, at certain seasons breaks up into a number of separate cells which develop a tuft of cilia and escape from the sheath.
This is also caused by the presence of a microbe, of which the virus can also be attenuated, and by inoculation of this weakened virus the animal rendered immune.
By inoculating first with a weak virus and then with others which were stronger and stronger, he was able completely to protect oxen either from the effects of inoculation with the strongest virus or from infection through contact with other animals suffering from the disorder.
To begin with, Pasteur, in studying the malady in dogs, came to the conclusion that the virus had its seat in the nerve centres, and he proved that the injection of a portion of the matter of the spinal column of a rabid dog into the body of a healthy one produces in the latter with certainty the symptoms of rabies.
H.) protection against plague; (2) on the comparative liability of each fluid to contamination; and (3) on the probable origin of tetanus virus in the Malkowal cases.
At Hubli, where nearly the whole population was inoculated between the lath of May and the 27th of September ' The system of inoculation against plague with a fluid prepared from sterilized virus of the disease was introduced in India by Professor Haffkine early in 1897.
The next step was to endeavour so to modify and weaken the virus as to enable it to be used as a preventive or as an antitoxin.