One of the earliest, if not the earliest, was the investigation, published in 1830, which proved the polymerism of cyanic and cyanuric acid, but the most famous were those on the oil of bitter almonds (benzaldehyde) and the radicle benzoyl (1832), and on uric acid (1837), which are of fundamental importance in the history of organic chemistry.
In health most of the nitrogenous waste in the body is eliminated as urea, but in gout uric acid is either formed in too great quantity or too little is eliminated, so that it tends to be deposited as urate of soda in the joints and other tissues.
The uric acid excreted in the urine (mostly in the form of urates) is markedly diminished.
Parasites, tuberculosis; (0) on the ground that the flesh of artificially fed animals is full of excretory substances, and that, therefore, under modern conditions, flesh-eating is injurious, and may be a cause of excretory substance and uric acid deposits or rapid tissue-destroying diseases in man; e.g.
Lithium salts render the urine alkaline and are in virtue of their action diuretic. They are much prescribed for acute or chronic gout, and as a solvent to uric acid calculi or gravel, but their action as a solvent of uric acid has been certainly overrated, as it has been shown that the addition of medicinal doses of lithium to the blood serum does not increase the solubility of uric acid in it.