Hence bromide of potassium - or bromide of sodium, which is possibly somewhat safer still though not quite so certain in its action - is used as a hypnotic, as the standard anaphrodisiac, as a sedative in mania and all forms of morbid mental excitement, and in hyperaesthesia of all kinds.
Lead salts are applied as lotions in conditions where a sedative astringent effect is desired, as in weeping eczema; in many varieties of chronic ulceration; and as an injection for various inflammatory discharges from the vagina, ear and urethra, the Liquor Plumbi Subacetatis Dilutum being the one employed.
Given internally, atropine does not exert any appreciable sedative action upon the nerves of pain.
The extreme pain and rapid swelling of the vocal cords - with threatened obstruction to the respiration - that characterize acute laryngitis may often be relieved by the sedative action of this drug upon the circulation.
Fraser proved that by substitution of molecules in certain compounds a stimulant could be converted into a sedative action; thus by the addition of the methyl group CH 2 to the molecule of strychnine, thebaine or brucine, the tetanizing action of these drugs is converted into a paralysing action.
In whooping-cough, when a sedative is required but a stimulant is also indicated, ammonium bromide is often invaluable.
Such a cough is relieved by the sedative action on the central nervous system.
The sedative effect of lead lotion in pruritus is well known.
Thus in the eye and ear, lotions containing an antiseptic, a sedative and an astringent are very generally used.