In 1745 the Capuchin mission finally collapsed after a revival had been attempted in 1741 by a party under Orazio della Penna, of which Cassiano Beligatti was chronicler.
The chief agents in their dispersal were the Doctor Orazio Melzi who possessed them in the last quarter of the 16th century; the members of a Milanese family called Mazzenta, into whose hands they passed in Orazio Melzi's lifetime; and the sculptor Pompeo Leoni, who at one time entertained the design of procuring their presentation to Philip II.
The ascent was first made in 1794 by Orazio Delfico from the Teramo side.
In 1715 Fathers Desideri and Freyre made their way from Agra, across the Himalayas, to Lhasa, and the Capuchin Friar Orazio della Penna resided in that city from 1735 until 1747.
This scholarly linguist, equipped with modern methods of scientific research, did not confine himself to the classical period like Csoma, but extended his ' The Capuchin friars who were settled in Lhasa for a quarter of a century from 1719 studied the language; two of them, Francisco Orazio della Penna, well known from his accurate description of Tibet, and Cassian di Macerata sent home materials which were utilized by the Augustine friar Aug.