During the reign of the pleasure-loving Leo, Cardinal Giulio had practically the whole papal government in his hands and displayed all the qualities of a good administrator; and when, on the death of Adrian VI.
After a considerable time spent in various cities and courts of Italy, where his learning already made him welcome, he accompanied Giulio de' Medici to Rome, where he was soon after appointed secretary to Leo X.
The old ducal palace - one of the largest buildings of its kind in Europe - was begun in 1302 for Guido Bonaccolsi, and probably completed in 1328 for Ludovico Gonzaga; but many of the accessory apartments are of much later date, and the internal decorations are for the most part the work of Giulio Romano and his pupils.
In conjunction with Cardinal Giulio de' Medici in the conclave of 1521-1522, he secured the election of Adrian Dedel, bishop of Tortosa, as Adrian VI.
The objects discovered are in the Museo di Papa Giulio at Rome.
The present Piazza Giulio Cesare marks the site of the ancient forum.
Cardinal Giulio de' Medeci, the cousin of that pope, had already exercised a decisive influence upon Catholic policy; and the tiara now fell to his lot.
In the same year, 1520, Machiavelli, at the instance of the cardinal Giulio de' Medici, received commission from the officers of the Studio pubblico to write a history of Florence.
At his death in 1519 Cardinal Giulio de' Medici (son of the Giuliano murdered in the Pazzi conspiracy) took charge of the government; he met with some opposition and had to play off the Ottimati against the Piagnoni, but he did not rule badly and maintained at all events the outward forms of freedom.
In 1494 Giulio went with them into exile; but, on Giovanni's restoration to power, returned to Florence, of which he was made archbishop by his cousin Pope Leo X., a special dispensation being granted on account of his illegitimate birth, followed by a formal declaration of the fact that his parents had been secretly married and that he was therefore legitimate.