In practical medicine the subsequent results of Behring and his followers have in diphtheria attained a signal therapeutical success.
Again, all accounts of diphtheria show a tendency on the part of the disease to recur in the same districts year after year.
Thus paralysis following diphtheria is in all probability due to a different toxin from that which causes the acute symptoms of poisoning or possibly to a modification of it sometimes formed in specially large amount.
The facts with regard to passive immunity were thus established and were put to practical application by the introduction of diphtheria antitoxin as a therapeutic agent in 1894.
Thus in diphtheria changes in both nerve cells and nerve fibres have been found, and in tetanus minute alterations in the nucleus and protoplasm of nerve cells.
Thus in cholera the bacteria are practically confined to the intestine, in diphtheria to the region of the false membrane, in tetanus to some wound.
Von Behring completed the sphere of the new study by his discovery of the antitoxins of diphtheria and tetanus.
On the whole Hungary is a healthy country, excepting in the marshy tracts, where intermittent fever and diphtheria sometimes occur with great virulence.
The most unhealthy period is from 1st May to 31st October, when there are, from time to time, outbreaks of typhoid, small-pox, diphtheria and other epidemics.
Epidemic outbreaks of other diseases - for instance, cholera, diphtheria and typhoid fever - are often preceded and followed by the prevalence of mild illness of an allied type; and t he true significance of this fact is one of the most important problems in epidemiology.