In diabetes mellitus, in which there is marked derangement in metabolism, extreme fatty changes are occasionally found in the organs, and the blood may be loaded with fat globules.
The first scientific attempt to employ portions of raw organs in the treatment of disease was made by Lauder Brunton in diabetes in 1873, sixteen years before Brown-Sequard's paper on the effect of testicular juice.
Combined with opium it is an efficient remedy in diabetes insipidus.
The waters are used in cases of liver affections, gout, diabetes and obesity; and the patients must conform during the cure to a strictly regulated diet.
It is said to be increased in saccharine diabetes and to be greatly diminished in starvation and wasting diseases.
In some skin diseases such as psoriasis, chronic eczema and acne indurata, phosphorus is very useful, and cases of diabetes mellitus and lymphadenoma have improved under some of its compounds.
In diabetes this organ seems to play a part which is not yet precisely determined; and one fell disease at least has been traced to a violent access of inflammation of this organ, caused perhaps by entry of foreign matters into its duct.
This is apt to be met with in oldish persons with diseased vessels and feeble heart-action, especially if the blood is rendered less nutritious by the presence of diabetes or of kidney disease.