From the fact that bacilli are hardly ever found in the blood of bubonic cases it may be inferred that they are arrested by the lymphatic glands next above the seat of inoculation, and that the fight - which is the illness - takes place largely in the bubo; in non-bubonic cases they are not so arrested, and the fight takes place in the general circulatory system, or in the lungs.
The action of quinine on the circulatory apparatus is not marked.
In different parts of the coelenteron the endoderm may be of three principal types - (i) digestive endoderm, the primitive type, with cells of large size and considerably vacuolated, found in the hydranth; some of these cells may become special glandular cells, without flagella or contractile processes; (2) circulatory endoderm, without vacuoles and without basal contractile processes, found in the hydrorhiza and hydrocaulus; (3) supporting endoderm (fig.
The circulatory system of Carinella is considerably different, being more lacunar and less restricted to definite vascular channels.
Modern oceanography has found means to calculate quantitatively the circulatory movements produced by wind and the distribution of temperature and salinity not only at the surface but in deep water.
No respiratory or circulatory organs are known.
Amongst these, the most important is fever with increased protein metabolism, attended with disturbances of the circulatory and respiratory systems. Nervous symptoms, somnolence, coma, spasms, convulsions and paralysis are of common occurrence.
Small doses of any of them dilate the blood vessels from an action on the vaso-motor centre in the medulla oblongata, as a result of which the heart beats more rapidly and the blood circulates more freely; but larger doses have a general depressing effect upon the circulatory system.
In the vast majority of cases the bacilli are in the lymphatic or the circulatory system, and aerial convection, even for a short distance, seems highly improbable.
Much light has been thrown upon the variations of arterial and venous blood pressures by Karl Ludwig (1816-1895) and his many followers: by them not only the diseases of the circulatory system itself are elucidated, but also those of other systems - the nervous, for instance - which depend intimately on the mechanical integrity of the circulation of the blood as well as on the chemical integrity of the blood itself.