Since the date mentioned the official style is Calabar simply.
They have been for several generations the middle men between the white traders on the coast and the inland tribes of the Cross river and Calabar district.
Calabar estuary is mainly formed by the Cross river (q.v.), but receives also the waters of the Calabar and other streams. The Rio del Rey creek at the eastern end of the estuary marks the boundary between (British) Nigeria and (German) Cameroon.
East of the Niger delta is that formed by the Imo or Opobo, Bonny and other streams, and still farther east is the Calabar estuary, mainly formed by the Cross river.
Physostigmine, the active principle of the Calabar bean, acts chiefly as a stimulant to voluntary and involuntary muscles, and at the same time exercises a depressing effect upon the spinal cord.
On the middle Cross river live the Akuna-kunas, an agricultural race, and in the Calabar region are the Efiks, Ibibios and Kwas.
Palm-oil, palm kernels, cocoa, copal, copra, Calabar beans, kola-nuts and ivory are the principal exports.
In the days of the colonial slave trade its African centre was the region about the mouths of the rivers Calabar and Bonny, whither the captive negroes were brought from great distances Africa.
The alkaloid calabarine is, on the other hand, a stimulant of the motor and reflex functions of the cord, so that only the pure alkaloid physostigmine and not any preparation of Calabar bean itself should be used when it is desired to obtain this action.
From that date until 1906 Calabar was the headquarters of the European administration in the Niger delta.