When iron is injected directly into a vein it depresses the heart's action, the blood pressure and the nervous system, and during its excretion greatly irritates the bowel and the kidneys.
The traffic crawled to a near standstill as Dean's blood pressure mounted, sure the 8:00 direct flight to Norfolk would leave without him.
Welch produced oedema of the lungs experimentally by increasing the pressure in the pulmonary vessels by ligature of the aorta and its branches, but this raised the blood pressure only about one-tenth of an atmosphere, while in some of Loeb's experiments the osmotic pressure, due to retained metabolic products, was equal to over thirty atmospheres.
It is now coming to be recognized that increase of blood pressure alone is not sufficient to account for all dropsical effusions.
Not only is the respiratory centre stimulated but the cardiac centre is acted upon both directly by the drug and indirectly for a time by the enormous rise in blood pressure due to the contraction of the arterioles all over the body.
For on the one hand knowledge of the fact that nitrite of amyl lessens blood pressure has led to the successful employment of other nitrites and bodies having a similar action, and on the other the knowledge that increased blood pressure tends to cause anginal pain leads to the prohibition of any strain, any food, any exposure to cold, and also of any medicines which would unduly raise the blood pressure.
Nitrite of amyl has the power of dilating the arteries; it has consequently been employed with much success in lowering the blood pressure and removing the pain in angina pectoris.