In using benzoyl chloride in this reaction the condensation is found to proceed better if a little ammonium chloride be added: 2C6H5 CNd-C6H5.0001 C6H5 C Cl OC C6H5 6 H 5 N C(C6H5):N The cyanidines behave as weak bases.
Acetyl and benzoyl derivatives of nicotine on hydrolysis do not yield nicotine, but an isomeric, inactive oily liquid (metanicotine).
Cocaine in which the benzoyl group is replaced by the cinnamyl group. aand 3-truxillines, named from their isolation from a coca of Truxillo (Peru), are two isomeric alkaloids which hydrolyse to ecgonine, methyl alcohol, and two isomeric acids, the truxillic acids, C18H1604.
Benzamide, C 6 H 5 CONH 2, is prepared by the action of benzoyl chloride on ammonia or ammonium carbonate, or from ethyl benzoate and ammonia.
One of the earliest, if not the earliest, was the investigation, published in 1830, which proved the polymerism of cyanic and cyanuric acid, but the most famous were those on the oil of bitter almonds (benzaldehyde) and the radicle benzoyl (1832), and on uric acid (1837), which are of fundamental importance in the history of organic chemistry.
The alkaloid is a strong base and is very readily oxidized; chromic acid converts it into normal butyric acid and ammonia; hydrogen peroxide gives aminopropylvalerylaldehyde, NH 2 CH(C 3 11 7) (CH2)3 CHO, whilst the benzoyl derivative is oxidized by potassium permanganate to benzoyl-a-aminovaleric acid, C 6 H 5 CO NH CH(C 3 H 7) (CH 2)3 COOH.
Similarly he represented the reactions investigated by Liebig and Wehler on benzoyl compounds as double decompositions.
An alternative method consists in converting it into ethyl benzoate by shaking with benzoyl chloride and caustic soda.
T' rhos, horse, o15pov, urine), benzoyl glycocoll or benzoyl amidoacetic acid, C 9 H 9 NO 3 or C 6 H 5 CO NH CH 2 CO 2 H, an organic acid found in the urine of horses and other herbivorae.
It may be prepared by distilling calcium benzoate; by condensing benzene with benzoyl chloride in the presence of anhydrous aluminium chloride; by the action of mercury diphenyl on benzoyl chloride, or by oxidizing diphenylmethane with chromic acid.