With severe anguish or desperate battles
- in a very painful manner
- With extreme anguish or desperate struggles.
(adv.) With severe anguish or desperate battles.
And all the while, jet after jet of white smoke was agonizingly shot from the spiracle of the whale, and vehement puff after puff from the mouth of the excited headsman; as at every dart, hauling in upon his crooked lance (by the line attached to it), Stubb straightened it again and again, by a few rapid blows against the gunwale, then again and again sent it into the whale.