A severe birth problem that impacts the forming of the bones, vaginal organs, and facial features. The name "campomelic" arises from the Greek terms indicating "bent limb." Actual popular features of the illness usually feature bowing associated with lengthy bones associated with legs and sometimes the arms, characteristic dimpling of the skin throughout the unusual bones, reduced legs, underdeveloped neck, dislocated hips, uncommonly rotated feet (clubfeet), and an abnormal range ribs. Unique facial functions consist of a little chin, prominent eyes, and a flattened face. Maldevelopment associated with the airway in affected people can cause difficulty breathing.