meaning of Attenuated familial adenomatous polyposis

Attenuated familial adenomatous polyposis meaning in Medical Dictionary

An inherited predisposition to colorectal disease described as less than 100 adenomatous polyps in the colon and colon. It is stated to be attenuated because there tend to be fewer polyps than in classic familial adenomatous polyposis (FAP). People who have attenuated familial adenomatous polyposis (AFAP) in addition are generally older in the diagnosis of their polyps (average chronilogical age of 44 many years) and cancer (average chronilogical age of 56 years), 10 to 15 many years later compared to classic FAP. The proper region of the colon tends to be associated with AFAP and rectal participation is rare. AFAP is sent in an autosomal dominant way.