a unique antibody this is certainly directed against structures in the nucleus associated with mobile. Antinuclear antibodies (ANAs) are observed in clients whose defense mechanisms is predisposed to cause swelling against unique human body tissues. Antibodies which can be directed against one's very own areas are described as autoantibodies. The propensity for the immunity system to exert effort against its body is referred to as autoimmunity. ANAs suggest the feasible existence of autoimmunity.