meaning of Anthracycline

Anthracycline meaning in Medical Dictionary

a part of a family of chemotherapy medicines which can be additionally antibiotics. The anthracyclines react to avoid cellular division by disrupting the dwelling associated with DNA and end its purpose. They are doing therefore in 2 techniques: (1) they intercalate to the base pairs when you look at the DNA small grooves; and (2) they cause no-cost radical harm of ribose within the DNA. The anthracyclines are generally utilized in leukemia treatment. The anthracyclines consist of daunorubicin (Cerubidine), doxorubicin (Adriamycin, Rubex), epirubicin (Ellence, Pharmorubicin), and idarubicin (Idamycin).