An inherited condition characterized by too little the alpha-1 antitrypsin protease inhibitor. Alpha-1 antitrypsin deficiency results in damage of numerous body organs, particularly the lung and liver. Symptoms may become evident at a tremendously early age or anytime later, manifesting as shortness of breath due to emphysema or as liver symptoms such as for example jaundice, fatigue, fluid in the stomach, mental changes, or gastrointestinal bleeding. Treatment options consist of, for lung condition, replacement associated with the lacking alpha-1 antitrypsin. Avoidance of cigarette smoking as well as other lung irritants is an important part of administration. Remedy for the liver infection is liver transplant. Also called protease inhibitor 1 deficiency.