An historic design for the therapy of genetic disease. In a time (the 1950s) whenever passed down problems were generally regarded as hopeless, this progressive hereditary (autosomal recessive) illness of children had been found treatable. Acrodermatitis enteropathica is characterized by the multiple event of skin inflammation (dermatitis) and diarrhea. The skin on cheeks, elbows and legs and tissue in regards to the lips and rectum tend to be inflamed. There was in addition balding regarding the head, eyebrows and eyelashes, delayed wound healing and recurrent microbial and fungal infections considering immune deficiency.